Web遗传性因子Ⅺ缺乏症由Rosenthal等首先报道于1953年，当时命名为血友病C，但现在一般称为因子Ⅺ缺乏症。 本病多见于犹太人后裔，其杂合子发生率可达2%～13%，纯合子发生率约0. 1%。 但在美国约半数因子Ⅺ缺乏症没有犹太血统。 一般人群中本病发生率差别很大，估计平均约为1/10万，也有人估计占血友病的2%～3%。 我国1986～1988 年24个省市37 … Web遗传性因子Ⅷ缺乏症 本病罕见，为常染色体隐性遗传，男女均可患病，男略多于女，往往有近亲婚配史。 纯合子患者血浆中因子Ⅷ低于正常人的1%时则发生出血。 临床表现为延迟性出血，新生儿患者以脐带残端 出血 为多见，其次为皮下出血，血肿及外伤后持久出血不止，或外伤后延迟至12～36小时后才出血，伤口愈合不良。 自发性出血或关节腔出血少见，严 …
Factor VII Deficiency: Causes, Symptoms, and …
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因子IX缺乏(血友病B):实践要点，背景，病理生理学
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