WebJun 2, 2024 · FSTL1 is a cardioprotective factor [ 4 ], pro-fibrotic agent [ 5 ], and a bi-directional regulator of tumor based upon the origin of the tumorigenic cell line [ 6 ]. Asthmatic patients express high levels of FSTL1 in plasma and bronchoalveolar lavage fluid (BALF) compared with health subjects [ 7 ]. WebOct 17, 2011 · The monocyte cell line U937, which does not express FSTL1, was transfected with a plasmid encoding FSTL1 and stimulated with phorbol myristate acetate and lipopolysaccharide. Cell supernatants were assayed for IL-6, IL-8, monocyte chemotactic protein 1 (MCP-1), and FSTL1 by enzyme-linked immunosorbent assay.
FSTL1 promotes liver fibrosis by reprogramming macrophage ... - PubMed
WebMar 24, 2024 · The FSTL1 protein was significantly less in lung tissues of Fstl1 +/− mice, and the increased FSTL1 protein after silica treatment was reduced in Fstl1 +/− mice (Fig. 2a). WebAug 5, 2024 · Follistatin-like 1 (FSTL1), a TGF-β-induced matricellular protein, is documented as an intrinsic regulator of proliferation and differentiation in MSCs. In the present study, we characterized the potential role of FSTL1 in MSC-based anti-fibrotic therapy and further elucidated the mechanisms underlying its action. Methods my ex asked me when will i have a boyfriend
Anti-FSTL1 Antibodies Invitrogen - Thermo Fisher Scientific
WebNov 15, 2024 · Follistatin-like 1 (FSTL1) has been widely reported as a proinflammatory mediator in different fibrosis-related and inflammatory diseases. Here we show FSTL1 expression to be closely correlated with activated fibroblasts and to be elevated in regenerative, fibrotic, and disease liver states in various mouse models. WebMar 21, 2024 · FSTL1 is a potential mediator of inflammation and insulin resistance in obesity. These results suggest that FSTL-1 may act on the NLRP3 inflammasome to … WebApr 11, 2011 · Follistatin-like 1 (Fstl1), first identified as a TGF-β1–inducible gene (), encodes a secreted extracellular glycoprotein belonging to the Fst-SPARC family, whose … offroadforen community