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Iron-sulfur cluster-binding protein ykgf

Iron–sulfur clusters are molecular ensembles of iron and sulfide. They are most often discussed in the context of the biological role for iron–sulfur proteins, which are pervasive. Many Fe–S clusters are known in the area of organometallic chemistry and as precursors to synthetic analogues of the biological clusters (see Figure). It is believed that the last universal common an… WebAbstract Iron-sulfur [Fe-S] clusters are ubiquitous and evolutionary ancient prosthetic groups that are required to sustain fundamental life processes. Owing to their remarkable structural plasticity and versatile chemical/electronic features [Fe-S] clusters participate in electron transfer, substrate binding/activation, iron/sulfur storage, regulation of gene …

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WebIron-sulfur clusters have a remarkable facility for conversion and interconversion in both the free and protein-bound conditions, supporting the concept that they are modular structures. They also undergo ligand exchange reactions and oxidative degradation, both of which are biologically significant. WebMar 24, 2009 · Protein Submitted name: Iron-sulfur cluster-binding protein Gene ykgF Organism Bacillus cereus (strain Q1) Status Unreviewed-Annotation score: Annotation … frigidaire filter microwave https://solrealest.com

Iron-sulfur protein - Wikipedia

WebOct 19, 2024 · Our data indicate that the iron-sulfur cluster is critical for interaction of human Polε with DNA. Probably, abrogated DNA binding is responsible for the loss of both activities in hPolε CD.... WebIron–sulfur clusters are ubiquitous in modern biological systems, serving multiple purposes including protein structural stabilization, electron transfer, substrate binding and … WebDOI: 10.1016/j.tem.2009.12.006 Abstract Iron-sulfur (Fe/S) proteins are a class of ubiquitous components that assist in vital and diverse biochemical tasks in virtually every living cell. These tasks include respiration, iron homeostasis and gene expression. frigidaire filter pop out recall

Identification of Iron-Sulfur (Fe-S) and Zn-binding Sites Within ...

Category:Enzymatic and Chemical In Vitro Reconstitution of Iron-Sulfur Cluster …

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Iron-sulfur cluster-binding protein ykgf

The iron-sulfur cluster is essential for DNA binding by …

Web2 days ago · Introduction. Iron is an essential trace element that functions as a cofactor in a wide variety of biological processes, such as oxygen delivery, ATP production, and DNA synthesis and repair, by binding to proteins (1, 2).However, excess iron is toxic owing to its ability to promote the generation of reactive oxygen species (3, 4).Ferroptosis (5), a type … WebGO:0051536 ! iron-sulfur cluster binding GO:0051539 ! 4 iron, 4 sulfur cluster binding GO:0055114 ! oxidation-reduction process GO:0003674 ! molecular function GO:0005575 ! …

Iron-sulfur cluster-binding protein ykgf

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Webthan a [2Fe-2S] cluster. The site-directed mutation experi-ments suggest that the four cysteine residues are involved in the ligation of this [4Fe-4S] cluster. This iron-sulfur cluster has a unique feature, very high sensitivity to oxygen exposure, which has not been observed on other EPR-detectable iron-sulfur clusters in NDH-1/complex I. WebOct 8, 2024 · show that thousands of novel binding sites for iron-sulfur (Fe-S) clusters and zinc ions can be identified ... sensing iron and oxygen [10-12], while Zn binding is …

WebDec 14, 2024 · Two forms of iron–sulfur clusters binding have been identified in pigeon MagR and showed different magnetic properties: [3Fe–4S]-MagR appears to be superparamagnetic and has saturation...

WebJun 6, 2016 · Results: We developed a web server to predict iron–sulfur proteins from protein sequence (s). This tool, called MetalPredator, is able to process complete proteomes rapidly with high recall and precision. Availability and Implementation: The web server is freely available at: http://metalweb.cerm.unifi.it/tools/metalpredator/. WebJul 23, 2024 · The relevance of this approach is still testified by (1) its wide use to reconstitute iron-sulfur proteins as shown by papers in recent years: ISCU , Chromokinesin, KIF4A , FNR, and NsrR , and (2) the ability to carry out eukaryotic Fe-S cluster reconstitution by the well-characterized prokaryotic systems and/or its essential components such as ...

WebBinding site: 111 [4Fe-4S] cluster 1 (UniProtKB ChEBI) PROSITE-ProRule annotation. Sequence: C: Binding site: 114 ... PTHR10849 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL 1 hit; PROSITE. View protein in PROSITE; PS00198 4FE4S_FER_1 2 hits; PS51379 4FE4S_FER_2 2 hits; Pfam. View protein in Pfam;

WebApr 13, 2024 · HIGHLIGHTS. who: Simone Ciofi-Baffoni and Claudia Andreini from the Magnetic Resonance Center CERM, University of Florence, Via Luigi Sacconi, Sesto Fiorentino, FI, Italy have published the research work: The Intriguing Role of Iron-Sulfur Clusters in the CIAPIN1 Protein Family, in the Journal: Inorganics 2024, 52 of /2024/ what: … fb messenger notification but no messageWebNational Center for Biotechnology Information frigidaire flashing hWebIron-sulfur clusters are perfect for this task, since they form a unique delocalized system for storing an electron that may be tuned by the surrounding amino acids in a protein. Two types of clusters are particularly common: a square arrangement of two irons and two sulfurs, and a distorted cube composed of four irons and four sulfurs. fb messenger default themeWebNov 5, 2024 · IscR (iron-sulfur cluster regulator) is an iron-dependent regulator of isc-suf genes and other genes with a role in iron metabolism. ... Gel-retardation assays showed the binding of regulatory proteins to individual promoters. Our results demonstrated that several promoters in a sense and antisense direction influenced isc-suf expression and ... fb messenger edit automatic messagesWebJan 31, 2024 · Iron sulfur proteins (Fe-S) are ancient structures present in archaebacteria and are involved in central metabolic functions in these ancient organisms (Iwasaki, Archaea 2010:1, 2010). From an evolutionary perspective, Fe-S clusters originated early on during protein evolution; with the aid of an inducible and robust antioxidant defense system ... frigidaire fhww122wce specsWebIron–sulfur (Fe/S) clusters (ISCs) are redox-active protein cofactors that their synthesis, transfer, and insertion into target proteins require many components. Mitochondrial ISC … fb messenger for windows 11WebFeb 8, 2024 · The iron-sulfur (Fe-S) proteomic platform the team developed allowed them to gain a greater insight into the dynamics of iron-sulfur cluster delivery and binding, according to Professor of... fb messenger how to delete all conversations