Jay shendure h index
WebJay Shendure, PhD. Co-Founder & Scientific Advisor ... combinatorial indexing for single cell analyses; and whole organism lineage tracing. He is the recipient of the 2012 Curt Stern Award from the American Society of Human Genetics, the 2013 FEDERAprijs, a 2013 NIH Director's Pioneer Award, and the 2014 HudsonAlpha Life Sciences Prize. ... Web13 nov. 2024 · Two papers now present a pooled approach using three levels of combinatorial indexing to examine the single-cell gene expression and chromatin landscapes from 15 organs in fetal samples. Cao et al. focus on measurements of RNA in broadly distributed cell types and provide insights into organ specificity.
Jay shendure h index
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WebAbstract To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile the transcriptomes of single cells or nuclei, termed sci-RNA-seq (single-cell combinatorial indexing RNA sequencing). WebJay Shendure MD, PhD. Jay Shendure. Genome Sciences. Professor. Email: [email protected] Phone: 206.685.8543. The primary mission of our lab is to develop …
Web20 feb. 2024 · Using single-cell combinatorial indexing, we profiled the transcriptomes of around 2 million cells derived from 61 embryos staged between 9.5 and 13.5 days of gestation, in a single experiment.... Web13 nov. 2024 · We generated human cell atlases of chromatin accessibility and gene expression in fetal tissues. For chromatin accessibility, we devised a three-level …
Web5 dec. 2024 · Single-cell combinatorial indexing (sci-) methods use split-pool barcoding to specifically label the molecular contents of large numbers of single cells or nuclei ().Samples can be barcoded by these same indices, e.g., by placing each sample in its own well during reverse transcription in sci-RNA-seq (21, 25), but such enzymatic labeling at the scale of … WebJay Shendure's 707 research works with 86,296 citations and 9,466 reads, including: Multiplex, single-cell CRISPRa screening for cell type specific regulatory elements
Web5 nov. 2024 · “Today we release in @biorxivpreprint a pair of related methods, DNA Ticker Tape & ENGRAM, for multiplex, temporally ordered genomic recording of cell lineage histories, enhancer & signal transduction activities, respectively led by the brilliant @_Choi_Junhong & @wchenomics 1/25” how can we save the earthWeb1 oct. 2008 · Shendure J 1, Ji H. Author information. Affiliations. 1 author. 1. Department of Genome Sciences, University of Washington, Seattle, Washington 98195-5065, USA. ORCIDs linked to this article. Shendure J, 0000-0002-1516-1865, University of Washington; Nature Biotechnology, 01 Oct 2008, 26(10 ... how can we save sloths from extinctionWeb25 sept. 2015 · Advances in DNA sequencing have enabled the identification of human germline and somatic mutations at a genome-wide scale.These studies have confirmed, refined, and extended our understanding on the origins, mechanistic basis, and empirical characteristics of human mutations, including both replicative and nonreplicative errors … how can we save the axolotlWebJay Shendure, M.D./Ph.D. - Publications. Affiliations: Genome Sciences. University of Washington, Seattle, Seattle, WA. Tree Info Similar researchers PubMed Report error. … how can we save the maldivesWeb19 feb. 2024 · Samples were indexed in a final PCR using standard Nextera P5 index primers of the form: ... Jay Shendure and Cole Trapnell: These authors jointly directed … how can we save the nhsWeb17 aug. 2024 · On Thursday, Dr. Shendure and his colleagues published a report describing a speedy new method for taking such a cell census. Instead of inspecting one cell at a time, they measured the activity ... how can we save the black footed ferretWeb22 mai 2015 · We applied combinatorial cellular indexing to measure chromatin accessibility in thousands of single cells per assay, circumventing the need for … how can we save the great salt lake