WebMar 13, 2024 · Preservation of the peritoneal membrane is an essential determinant of the long-term outcome of peritoneal dialysis (PD). Epithelial-to-mesenchymal transition (EMT) plays a central role in the pathogenesis of PD-related peritoneal membrane injury. We hypothesized that mitochondria may be implicated in the mechanisms that initiate and … WebAbstract Primary peritoneal malignant mesothelioma (MM) can demonstrate morphologic overlap with low-grade and high-grade tubo-ovarian serous neoplasms; it is also biologically and prognostically distinct from benign mesothelial proliferations. Currently, there is no single biomarker that can definitively distinguish these neoplasms.
Diseases of the Peritoneum SpringerLink
WebPeritoneal biopsies taken from PD patients show a reactive mesothelium with enlarged, weakly adhesive, degenerated mesothelial cells with a reduced number of microvilli and alterations in the number of endoplasmic reticulum and micropinocytotic vesicles ( Williams et al., 2002; Yung and Chan, 2012 ). WebOct 18, 2024 · Affected animals typically present for peritoneal fluid (ascites), which is characterized cytologically by reactive epithelial-like or mesenchymal-like cells. Cytologic distinction between reactive and neoplastic mesothelial cells is notoriously difficult. lancaster weir
Mesothelioma - Diagnosis and treatment - Mayo Clinic
WebLarge retroperitoneal masses: Slowly growing retroperitoneal masses, such as benign retroperitoneal neoplasms close to the serosal surface, may generate reactive changes in … WebPeritoneal wash. Pap stain. Cytology of reactive mesothelium, with typical features. The main causes of reactive mesothelium are infection, trauma and cancer. [3] Wright's stain. … Peritoneal mesothelioma is a rare type of cancer affecting your peritoneum. Your peritoneum is a membrane that lines your abdominal cavity and organs, like your liver and intestines. Like other types of mesothelioma, peritoneal mesothelioma can be related to prior asbestos exposure. See more The most common treatment for peritoneal mesothelioma is cytoreduction with hyperthermic intraperitoneal chemotherapy … See more Immunotherapy drugs called immune checkpoint inhibitors help your immune system locate and kill cancer cells. These types of drugs are commonly used to treat pleural mesothelioma. Your provider may also prescribe them to … See more You may receive systemic chemotherapy if you’re not able to have cytoreduction with HIPEC. Systemic chemotherapy drugs travel through your bloodstream to kill cancer cells … See more Some people with peritoneal mesothelioma may have genetic changes in their tumor cells that may be treated with targeted … See more help in marriage problems