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Phf21a

Web1. dec 2001 · Component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, KDM1A, RCOR1/CoREST and PHF21A/BHC80. The BHC complex may also contain ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I. In the complex, it interacts directly with HDAC1, HDAC2, HMG20B/BRAF35, KDM1A and RCOR1/CoREST. 3 publications WebPHF21A complex neurodevelopmental disorder. MONDO:0100038 AD Intellectual Disability and Autism GCEP Definitive 04/06/2024: Lumping & Splitting; Secondary Contributors; Lumping and Splitting is the process by which ClinGen curation groups determine which disease entity they will use for evaluation. ...

PHF21A - PHD finger protein 21A Gene MedChemExpress

Web25. sep 2013 · Labile Zn fingers (Zfs) in proteins contain Zn-bound thiolates that can react with electrophilic agents, causing Zn(2+) ejection and protein unfolding. Such labile Zfs have been shown to be Cys4 or Cys3His cores whose Zn-bound Cys have no hydrogen bonds. Our aim here is to identify labile Zfs in pro … WebPhf21a-KO应用于研究领域:DNA转录,行为/神经,细胞组成,死亡/衰老,细胞核,DNA结合蛋白,分子生物学,神经系统,细胞生物学,发育生物学 trace my phone with imei number https://solrealest.com

Monoclonal Anti-PHF21A antibody produced in mouse - Sigma-Aldrich

Web17. dec 2024 · PHF21A (PHD finger protein 21A) gene, located in the short arm of chromosome 11, encodes for BHC80, a component of the Lysine Specific Demethylase 1, Corepressor of REST (LSD1-CoREST) complex. BHC80 is mainly expressed in the human fetal brain and skeletal muscle and acts as a modulator of several neuronal genes during … WebSi tratta di una terapia innovativa che ha l’obiettivo di trattare una patologia agendo direttamente sulle sue basi genetiche, fornendo all’organismo una copia corretta di un gene difettoso o un altro gene che possa compensarne il malfunzionamento. Tra i principali strumenti utilizzati per trasferire materiale genetico ci sono i vettori virali: virus spogliati … WebChr: 25 Mapping Details/Browsers. Description. Predicted to enable chromatin binding activity. Acts upstream of or within face development. Predicted to be part of histone deacetylase complex. Is expressed in central nervous system; head; optic cup; otic vesicle; and pectoral fin. Orthologous to human PHF21A (PHD finger protein 21A). trace my roots

WikiGenes - Phf21a - PHD finger protein 21A

Category:Brain Sciences Free Full-Text New Insights into Potocki-Shaffer ...

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Phf21a

PHF21A expression as a biomarker of hepatocellular carcinoma ...

Web21. mar 2024 · PHF21A (PHD Finger Protein 21A) is a Protein Coding gene. Diseases associated with PHF21A include Intellectual Developmental Disorder With Behavioral … PHD finger protein 21A is a protein that in humans is encoded by the PHF21A gene. BHC80 is a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor … Zobraziť viac PHF21A has been shown to interact with: • HDAC1, • HMG20B, • Histone deacetylase 2, and • RCOR1. Zobraziť viac • Shi YJ, Matson C, Lan F, Iwase S, Baba T, Shi Y (2005). "Regulation of LSD1 histone demethylase activity by its associated factors". … Zobraziť viac • PHF21A+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine Zobraziť viac

Phf21a

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WebBiological context of PHF21A. The C-terminal region of human BHC80 containing PHD zinc-finger domain was capable of binding directly to each of five other components of BHC, and of organizing BHC mediating transcriptional repression . A possible role of BHC80 in spermatogenesis is also suggested . Web1. sep 2024 · PHF21A expression in 201 liver cancer samples and 129 adjacent normal tissues was detected by immunohistochemistry. The correlation between PHF21A …

WebBecause the PHF21A gene is important in brain development, many people who have PHF21A-related syndrome have: Autism; Intellectual disability; Seizures; Increased weight, … http://www.biofeng.com/gene/renyuan/PHF21A.html

http://www.pansmed.com/gene/2024/08/19/30663.html WebThe gene PHF21A (PHD finger protein 21A) is also referred to as BHC80 and forms a component of the BRAF-histone deacetylase complex, which is involved in the repression of target-gene transcription. The encoded protein is found to be essential for normal brain development and cognitive function. Disruption of this gene has been found to be ...

Web6. apr 2024 · A microdeletion encompassing PHF21A in an individual with global developmental delay and craniofacial anomalies

WebRappresentazione schematica della mioglobina.Quest'omologo proteico dell'emoglobina lega l'ossigeno nei muscoli. È la prima proteina la cui struttura è stata risolta con la cristallografia a diffrazione di raggi X da Max Perutz e John Kendrew. In chimica, le proteine (o protidi) sono macromolecole biologiche costituite da catene di amminoacidi legati uno … trace my recorded delivery letterWebPHF21A Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, PHF21A Genome Browser, PHF21A References. PHF21A - Explore an overview of PHF21A, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data. thermos ultimate series 500ml reviewWebView Gene Families for PHF21A_TARGET_GENES. The following table provides a functional overview of the MSigDB gene sets by categorizing their genes into a small number of carefully chosen "gene families". To categorize the genes in a gene set, use the gene set page or the Investigate Gene Sets page. thermos ultimate flask stopperWebLOVD: PHF21A; Liste de maladies. Rôle dans le phénotype de Syndrome de Potocki-Shaffer: ORPHA:52024 : Vérifié ... thermos ultimate flask 900ml reviewWeb21. mar 2024 · Clinical resource with information about PHF21A, Intellectual developmental disorder with behavioral abnormalities and craniofacial dysmorphism with or without … thermos ultralight bottleWeb22. okt 2024 · Background: PHF21A has been associated with intellectual disability and craniofacial anomalies based on its deletion in the Potocki-Shaffer syndrome region at 11p11.2 and its disruption in three patients with balanced translocations. In addition, three patients with de novo truncating mutations in PHF21A were reported recently. Here, we … trace my routethermos ultimate flask review