WebStrain Name: C57BL/6-Timd4 tm2(TIMD4) /Bcgen: Common Name : B-hTIM4 mice: Background: C57BL/6: Catalog number: 110837: Aliases : SMUCKLER, TIM4: NCBI Gene ID: 276891: Model validation. mRNA expression analysis. Strain specific analysis of TIM4 gene expression in wild-type C57BL/6 mice and B-hTIM4 mice by RT-PCR. Mouse TIM4 … Web17 mar 2024 · Targeted cytoplasmic components are sequestered by double-membrane vesicles named ... IL-23 activity in inflammation is associated with a unique gene ... We noticed that the resident TIM4 ...
Vitamin D regulates immunoglobulin mucin domain molecule …
Web21 feb 2006 · Status. UniProtKB unreviewed (TrEMBL) Organism. Homo sapiens (Human) Amino acids. 262. Protein existence. Evidence at transcript level. Annotation score. Web12 lug 2024 · Cavity-resident macrophages express high levels of Tim-4, a receptor for phosphatidylserine (PS), and this is associated with reduced numbers of CD8+T cells with tumor-reactive features in pleural effusions and peritoneal ascites from patients with cancer. meyers snow plow e60 manual
Synergistic effect of Tim4 and MFG-E8 null mutations on the …
WebTIM-4 (T cell; immunoglobulin; mucin-4), also known as SMUCKLER, is a 60 kDa member of the TIM family of immune regulating proteins. TIMs are type I transmembrane proteins … WebTargeted disruption of the Tim4 gene The Tim4-targeted mice were generated as custom order by Unitech (Kashiwa, Chiba, Japan). In brief, the Tim4 chromosomal gene was isolated from BAC clones of C57BL/6 mice, and its exon 1 and most of exon 2 were replaced by a coding sequence for Venus and neo gene (Fig. 1). Web9 feb 2024 · The sequences of Tim1 and Tim4 guide RNAs (gRNAs) were designed on the software program CRISPRdirect (Naito et al., 2015) as follows: 5′-TGGTCTGTATTGTTGTCGAGTGG-3′, located at exon 2 of Tim1 gene and 5′-GGTGTACTGCTGCCGTATAGAGG-3′, located at exon 2 of Tim4 gene. meyers snow plow manual